Polyquaternium-2
[CAS# 68555-36-2]

Identification

• Classification: Catalysts and additives >> Polymer
• Name: Polyquaternium-2
• Synonyms: Bis(2-chloroethyl) ether-1,3-bis[3-(dimethylamino)propyl]urea copolymer; Poly[bis(2-chloroethyl)ether 1,3-bis[3-(dimethylamino)propyl]urea] quaternized
• Molecular Formula: (C₁₁H₂₆N₄O)_n^.(C₄H₈Cl₂O)_n
• CAS Registry Number: 68555-36-2
• EC Number: 614-612-6

Properties

• Concentration: 62 wt. % in H2O
• Density: 1.13
• Boiling point: 105 ºC
• Refractive index: 1.468

Safety Data

• Hazard Symbols: GHS07;GHS09 Warning
• Hazard Statements: H317-H400-H410
• Precautionary Statements: P261-P272-P273-P280-P302+P352-P321-P333+P317-P362+P364-P391-P501

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Chronic hazardous to the aquatic environment	Aquatic Chronic	1	H410
Acute hazardous to the aquatic environment	Aquatic Acute	1	H400
Skin sensitization	Skin Sens.	1	H317
Chronic hazardous to the aquatic environment	Aquatic Chronic	2	H411
Chronic hazardous to the aquatic environment	Aquatic Chronic	3	H412

Discovory and Applicatios

Polyquaternium-2 is a synthetic polymer widely used in personal care products due to its cationic nature, which allows it to interact effectively with negatively charged surfaces like hair and skin. The compound belongs to the polyquaternium family, which consists of various polymers with quaternary ammonium groups. Polyquaternium-2, in particular, has gained attention for its excellent conditioning properties, making it a common ingredient in hair conditioners, shampoos, and skin-care formulations.

The discovery of Polyquaternium-2 can be traced back to the growing demand for polymers that could improve the texture and manageability of hair without causing buildup or irritation. Early research into cationic polymers showed that they could effectively neutralize the static charge on hair, leading to smoother, less frizzy hair. Polyquaternium-2, with its positively charged quaternary ammonium groups, was developed to meet this need, as it binds well to hair keratin, providing conditioning benefits that are long-lasting and resistant to washing.

In addition to its role in hair care, Polyquaternium-2 is also used in skin-care formulations. Its ability to form a protective film on the skin helps in moisturizing by reducing water loss. The film-forming properties of Polyquaternium-2 make it a valuable ingredient in lotions and creams, where it enhances the skin’s smoothness and hydration. Moreover, its gentle nature makes it suitable for use in products for sensitive skin, as it does not typically cause irritation.

One of the major applications of Polyquaternium-2 is in the formulation of leave-in conditioners and detangling sprays. Its cationic nature helps reduce hair breakage by smoothing the hair cuticle and reducing friction during combing. This leads to improved hair manageability, particularly for individuals with curly or coarse hair types. The polymer’s ability to reduce static charge also contributes to its effectiveness in anti-frizz products.

Polyquaternium-2 has also been explored for use in hair dyes and styling products. The polymer can enhance the adherence of dyes to the hair shaft, resulting in more vibrant and long-lasting color. In styling gels and mousses, Polyquaternium-2 provides hold and structure without leaving a sticky residue, improving the overall user experience.

As research continues, Polyquaternium-2 is expected to remain a key ingredient in personal care products, offering benefits such as conditioning, moisturizing, and film-forming properties across a range of applications.