Imidazole-epichlorohydrin copolymer
[CAS# 68797-57-9]

Identification

• Classification: Catalysts and additives >> Polymer
• Name: Imidazole-epichlorohydrin copolymer
• Synonyms: RaluPlate IME; RaluPlate MOME
• CAS Registry Number: 68797-57-9
• EC Number: 614-729-2
• SMILES: ClCC1CO1.c1c[nH]cn1

Safety Data

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Chronic hazardous to the aquatic environment	Aquatic Chronic	2	H411
Acute toxicity	Acute Tox.	4	H312
Skin irritation	Skin Irrit.	2	H315
Eye irritation	Eye Irrit.	2	H319
Chronic hazardous to the aquatic environment	Aquatic Chronic	1	H410
Acute toxicity	Acute Tox.	4	H302
Acute hazardous to the aquatic environment	Aquatic Acute	1	H400

Discovory and Applicatios

Imidazole-epichlorohydrin copolymer is a synthetic polymer formed by the reaction of imidazole, a heterocyclic organic compound, with epichlorohydrin, an epoxy compound. This copolymer is commonly used in various industrial and biomedical applications due to its unique properties, which include high chemical stability, water solubility, and the ability to form cross-linked structures.

The synthesis of imidazole-epichlorohydrin copolymer typically involves the reaction of imidazole with epichlorohydrin in the presence of a base, such as sodium hydroxide (NaOH). This reaction leads to the formation of the polymer through a process known as nucleophilic substitution, where the hydroxyl group of epichlorohydrin reacts with the nitrogen atom of imidazole, forming a covalent bond and creating the polymer backbone. The reaction can be carried out under controlled conditions to achieve the desired molecular weight and structure of the copolymer.

One of the key characteristics of imidazole-epichlorohydrin copolymer is its ability to form a cross-linked network when exposed to certain chemical agents or physical conditions. This cross-linking enhances the polymer's stability and strength, making it suitable for use in various applications where durability and resistance to chemical degradation are required. The imidazole groups in the polymer provide a high degree of chemical reactivity, allowing for further modification or functionalization of the polymer structure.

In the biomedical field, imidazole-epichlorohydrin copolymer is used in drug delivery systems, particularly in the design of hydrogels. The copolymer's water-soluble nature and its ability to form networks make it an ideal candidate for controlled drug release applications. The polymer can encapsulate therapeutic agents and release them gradually in response to changes in environmental conditions, such as pH or temperature. This property is particularly useful for targeted drug delivery, where the release of the drug can be controlled to match the needs of the patient.

In addition to its use in drug delivery systems, imidazole-epichlorohydrin copolymer is employed in various other biomedical applications, such as wound dressings and tissue engineering. Its biocompatibility and ability to form hydrogels make it suitable for applications where moisture retention and support for tissue regeneration are important.

The copolymer is also used in water treatment and purification processes. Its functional groups can interact with various contaminants, allowing the polymer to remove impurities from water. This makes it useful in the development of filtration systems, where the copolymer can act as a selective adsorbent for certain types of pollutants, including heavy metals or organic compounds.

Imidazole-epichlorohydrin copolymer also finds applications in the textile industry. Its ability to form films and coatings makes it suitable for use in the production of fabrics with specific properties, such as water resistance or antimicrobial activity. The copolymer can be applied to textiles as a coating, providing enhanced durability and functionality to the fabric.

In addition to its industrial and biomedical applications, imidazole-epichlorohydrin copolymer has potential use in catalysis and sensors. The imidazole groups in the polymer structure can act as active sites for catalysis, enabling the polymer to be used in various chemical reactions. Furthermore, the copolymer can be designed to interact with specific analytes, making it useful in the development of sensors for detecting gases or chemicals in the environment.

Despite its many beneficial properties, imidazole-epichlorohydrin copolymer must be handled with care, especially in its raw form. Epichlorohydrin, a component of the copolymer, is a toxic and potentially carcinogenic substance. Proper safety protocols should be followed during the synthesis and handling of the copolymer to minimize exposure to harmful chemicals.

In conclusion, imidazole-epichlorohydrin copolymer is a versatile material with a wide range of applications in industries such as medicine, water treatment, textiles, and catalysis. Its ability to form cross-linked networks and respond to environmental stimuli makes it a valuable material for controlled drug release, tissue engineering, and various other applications. However, care must be taken in its handling and synthesis to ensure safety due to the toxic nature of one of its components, epichlorohydrin.