Walphos SL-W006-1
[CAS# 849925-21-9]

Identification

• Classification: Chemical reagent >> Organic reagent >> Phosphine ligand
• Name: Walphos SL-W006-1
• Synonyms: (1S)-1-[(1S)-1-[Bis(3,5-dimethylphenyl)phosphino]ethyl]-2-[2-(diphenylphosphino)phenyl]ferrocene
• Molecular Formula: C₄₆H₄₄FeP₂
• Molecular Weight: 714.63
• CAS Registry Number: 849925-21-9
• SMILES: CC1=CC(=CC(=C1)P(C2=CC(=CC(=C2)C)C)C(C)[C]3[CH][CH][CH][C]3C4=CC=CC=C4P(C5=CC=CC=C5)C6=CC=CC=C6)C.[CH]1[CH][CH][CH][CH]1.[Fe]

Safety Data

• Hazard Symbols: GHS07 Warning
• Hazard Statements: H302-H315-H319-H335
• Precautionary Statements: P261-P305+P351+P338

Discovory and Applicatios

Walphos SL-W006-1 is a chemical compound that has made significant contributions to the field of organometallic chemistry, particularly in the realm of catalytic processes. This substance belongs to a class of phosphine ligands, which are crucial in facilitating a variety of chemical reactions. The unique properties of Walphos SL-W006-1 make it an essential tool in both academic research and industrial applications.

The discovery of Walphos SL-W006-1 stemmed from the ongoing quest to develop more efficient and selective ligands for metal-catalyzed reactions. Phosphine ligands are known for their ability to stabilize transition metals and influence their reactivity, making them indispensable in catalysis. Walphos SL-W006-1 was designed to enhance these properties, offering improved performance in various catalytic transformations.

One of the primary applications of Walphos SL-W006-1 is in asymmetric catalysis. Asymmetric catalysis is a critical technique for the synthesis of chiral molecules, which are important in the pharmaceutical industry. The ability of Walphos SL-W006-1 to form stable complexes with transition metals enables it to catalyze reactions with high enantioselectivity. This characteristic is particularly valuable in the production of chiral drugs and other fine chemicals where precise control over stereochemistry is required.

In addition to asymmetric catalysis, Walphos SL-W006-1 has demonstrated effectiveness in cross-coupling reactions. Cross-coupling reactions, such as Suzuki, Heck, and Sonogashira couplings, are essential for constructing complex organic molecules. The ligand's ability to enhance the activity and selectivity of transition metal catalysts in these reactions makes it a valuable asset for both synthetic chemists and industrial manufacturers. The high efficiency and selectivity provided by Walphos SL-W006-1 contribute to more sustainable and cost-effective processes in organic synthesis.

Another notable application of Walphos SL-W006-1 is in the field of polymerization. The compound has shown promise in facilitating the polymerization of various monomers, leading to the development of advanced materials with tailored properties. The role of Walphos SL-W006-1 in polymerization reactions highlights its versatility and potential for innovation in material science.

The development of Walphos SL-W006-1 represents a significant advancement in ligand chemistry. By optimizing the electronic and steric properties of the phosphine ligand, researchers have been able to enhance the performance of metal-catalyzed reactions. This advancement underscores the importance of ligand design in improving catalytic efficiency and expanding the scope of chemical reactions.

In summary, Walphos SL-W006-1 is a valuable chemical substance with broad applications in organometallic chemistry. Its role in asymmetric catalysis, cross-coupling reactions, and polymerization highlights its significance in both academic research and industrial processes. The discovery and development of this compound exemplify the ongoing efforts to advance catalysis and materials science.