Diethylcarbamazine
[CAS# 90-89-1]

Identification

• Classification: API >> Antiparasitic drug >> Resistance to filariasis and anti-leishmaniasis
• Name: Diethylcarbamazine
• Synonyms: Ditrazine base; Ethodryl; N,N-Diethyl-4-methyl-1-piperazinecarboxamide; Notezine; RP 3799; Spatonin
• Molecular Formula: C₁₀H₂₁N₃O
• Molecular Weight: 199.29
• CAS Registry Number: 90-89-1
• EC Number: 202-023-3

Properties

• Solubility: Slightly soluble (2.2 g/L) (25 ºC), Calc.^*
• Density: 1.013±0.06 g/cm³ (20 ºC 760 Torr), Calc.^*
• Melting point: 65-67 ºC^**
• Boiling point: 127-129 ºC (10 Torr)^***
• Flash point: 116.6±17.7 ºC, Calc.^*

^* Calculated using Advanced Chemistry Development (ACD/Labs) Software V11.02 (©1994-2014 ACD/Labs)

^** Sugimoto, Norio; JP 39028551 B4 1964.

^*** Gauss, Walter; DE 923967 1955.

Safety Data

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Acute toxicity	Acute Tox.	4	H302
Eye irritation	Eye Irrit.	2A	H319
Skin irritation	Skin Irrit.	2	H315
Specific target organ toxicity - single exposure	STOT SE	3	H335