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4-(Hydroxymethyl)-5-methyl-1,3-dioxol-2-one
[CAS# 91526-18-0]

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Identification
Classification Organic raw materials >> Ketone compound
Name 4-(Hydroxymethyl)-5-methyl-1,3-dioxol-2-one
Molecular Structure CAS # 91526-18-0, 4-(Hydroxymethyl)-5-methyl-1,3-dioxol-2-one
Molecular Formula C5H6O4
Molecular Weight 130.10
CAS Registry Number 91526-18-0
EC Number 839-946-1
SMILES CC1=C(OC(=O)O1)CO
Properties
Density 1.4±0.1 g/cm3, Calc.*
Index of Refraction 1.494, Calc.*
Boiling Point 213.8±32.0 ºC (760 mmHg), Calc.*
Flash Point 92.8±18.6 ºC, Calc.*
* Calculated using Advanced Chemistry Development (ACD/Labs) Software.
Safety Data
Hazard Symbols symbol   GHS07 Warning    Details
Hazard Statements H302-H315-H319-H335    Details
Precautionary Statements P261-P264-P264+P265-P270-P271-P280-P301+P317-P302+P352-P304+P340-P305+P351+P338-P319-P321-P330-P332+P317-P337+P317-P362+P364-P403+P233-P405-P501    Details
Hazard Classification
up    Details
HazardClassCategory CodeHazard Statement
Skin irritationSkin Irrit.2H315
Eye irritationEye Irrit.2H319
Specific target organ toxicity - single exposureSTOT SE3H335
Acute toxicityAcute Tox.4H302
SDS Available
up Discovory and Applicatios
4-(Hydroxymethyl)-5-methyl-1,3-dioxol-2-one, also known as 4-hydroxy-5-methyl-1,3-dioxol-2-one, is a heterocyclic compound featuring a dioxolane ring structure. The compound is a member of the family of dioxolones, which are widely studied for their chemical and biological properties. The synthesis and applications of this compound have been explored in various contexts, particularly in the development of materials, pharmaceuticals, and as an intermediate in organic synthesis.

The discovery of 4-(Hydroxymethyl)-5-methyl-1,3-dioxol-2-one is tied to the broader exploration of dioxolane derivatives. Dioxolanes, in general, have attracted attention due to their ability to serve as building blocks for the synthesis of a variety of other chemical entities, including polymers, biologically active compounds, and functional materials. The compound itself is notable for containing both hydroxymethyl and methyl groups, which contribute to its chemical reactivity and make it an important intermediate in synthetic chemistry.

One of the primary applications of 4-(Hydroxymethyl)-5-methyl-1,3-dioxol-2-one lies in organic synthesis, where it is used as a key intermediate in the preparation of other more complex organic molecules. Its functional hydroxymethyl group allows for the introduction of further chemical modifications, making it a versatile precursor in the synthesis of various derivatives. For example, it has been used in the development of polymeric materials and as part of the synthesis of other heterocyclic compounds.

In addition to its role in chemical synthesis, the compound has also been studied for its potential biological applications. The presence of the hydroxymethyl group and the dioxolane ring structure may confer unique properties, such as the potential for interactions with biological molecules. However, the compound’s biological activity has been less extensively explored compared to other more well-known dioxolane derivatives, and most of the research has focused on its utility in synthetic chemistry.

Furthermore, 4-(Hydroxymethyl)-5-methyl-1,3-dioxol-2-one has been evaluated for its reactivity in various conditions. The compound’s ability to participate in ring-opening reactions, as well as other types of nucleophilic substitutions, is an area of interest in synthetic organic chemistry. These reactions make it useful in a range of applications, from the preparation of more complex organic molecules to its incorporation into larger macromolecular structures.

Despite its relatively narrow scope of research compared to other chemical compounds, 4-(Hydroxymethyl)-5-methyl-1,3-dioxol-2-one continues to be a subject of study for its potential applications in organic chemistry and material science. Its role in the synthesis of other chemicals and materials underscores its importance in both academic research and industrial applications.

In conclusion, 4-(Hydroxymethyl)-5-methyl-1,3-dioxol-2-one is a heterocyclic compound with applications primarily in organic synthesis and materials science. Its chemical structure, featuring a dioxolane ring with hydroxymethyl and methyl substituents, allows it to serve as a versatile intermediate in the preparation of various organic molecules and functional materials. Further research into its potential biological and industrial applications is ongoing, with the compound offering valuable insights into the chemistry of dioxolane derivatives.
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