Brequinar
[CAS# 96187-53-0]

Identification

• Classification: API >> Antineoplastic agents
• Name: Brequinar
• Synonyms: BPQ; Biphenquinate; 6-Fluoro-2-(2'-fluoro[1,1'-biphenyl]-4-yl)-3-methyl-4-quinolinecarboxylic acid
• Molecular Formula: C₂₃H₁₅F₂NO₂
• Molecular Weight: 375.37
• CAS Registry Number: 96187-53-0
• EC Number: 887-847-7

Properties

• Solubility: Insoluble (2.4E^-5 g/L) (25 ºC), Calc.^*
• Density: 1.319±0.06 g/cm³ (20 ºC 760 Torr), Calc.^*
• Melting point: 355-357 ºC (N,N-dimethylformamide water )^**

^* Calculated using Advanced Chemistry Development (ACD/Labs) Software V11.02 (©1994-2013 ACD/Labs)

^** Ackerman, Neil Richard; EP 339485 A1 1989.

Safety Data

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Eye irritation	Eye Irrit.	2A	H319
Specific target organ toxicity - single exposure	STOT SE	3	H335
Skin irritation	Skin Irrit.	2	H315
Acute toxicity	Acute Tox.	4	H332
Acute toxicity	Acute Tox.	4	H302
Acute toxicity	Acute Tox.	4	H312