3-(Dimethoxymethylsilyl)-1-propanol
[CAS# 99697-20-8]

Identification

• Classification: Pharmaceutical intermediate >> Heterocyclic compound intermediate >> Pyrimidine compound >> Alcohol
• Name: 3-(Dimethoxymethylsilyl)-1-propanol
• Molecular Formula: C₆H₁₆O₃Si
• Molecular Weight: 164.27
• CAS Registry Number: 99697-20-8
• SMILES: COC(OC)[SiH2]CCCO

Properties

• Density: 0.946 g/mL
• Boiling Point: 192.7±40.0 ºC (760 mmHg), Calc.^*, 79 ºC
• Flash Point: 70.4±27.3 ºC, Calc.^*, 62 ºC

^* Calculated using Advanced Chemistry Development (ACD/Labs) Software.

Discovory and Applicatios

3-(Dimethoxymethylsilyl)-1-propanol is an organosilicon compound that features a propanol backbone with a dimethoxymethylsilyl group attached to the terminal carbon. This structure imparts unique properties to the compound, making it valuable in various industrial applications. The discovery of this compound emerged from ongoing research into organosilicon chemistry, which has expanded significantly since the mid-20th century as scientists explored the functional versatility of silicon-containing compounds.

The synthesis of 3-(dimethoxymethylsilyl)-1-propanol typically involves the reaction of propanol with chlorodimethylsilane or related silane reagents in the presence of a suitable catalyst. This synthetic route allows for the incorporation of the silane moiety into the alcohol framework, producing a compound that possesses both hydroxyl and silyl functionalities. The presence of the dimethoxymethylsilyl group enhances the compound's hydrophobicity while maintaining some degree of hydrophilicity due to the alcohol functional group, rendering it suitable for various applications.

One of the primary applications of 3-(dimethoxymethylsilyl)-1-propanol is in the field of coatings and adhesives. Its silane functionality provides excellent adhesion properties to a variety of substrates, including metals, glass, and plastics. As a result, it is commonly used as a coupling agent in formulations aimed at improving the durability and performance of coatings. The compound's ability to promote bonding between dissimilar materials makes it particularly useful in automotive and construction industries, where high-performance adhesives are required.

In addition to its use in coatings, 3-(dimethoxymethylsilyl)-1-propanol is also employed in the formulation of silicone elastomers. These materials benefit from the incorporation of organosilicon compounds, which enhance their flexibility, heat resistance, and overall durability. The unique properties of this compound contribute to the performance of silicone-based products in various applications, including medical devices, consumer goods, and industrial components.

Another area of application for 3-(dimethoxymethylsilyl)-1-propanol is in the production of modified silica materials. The silane group facilitates the functionalization of silica surfaces, leading to materials with tailored properties for specific uses. These modified silica products can find applications in catalysis, chromatography, and as fillers in composite materials.

Safety considerations are essential when working with 3-(dimethoxymethylsilyl)-1-propanol, as with any chemical compound. It is crucial to follow proper handling protocols to mitigate any potential risks associated with exposure. Regulatory agencies provide guidelines to ensure that the use of this compound in various applications adheres to safety standards.

Recent research continues to investigate the potential of 3-(dimethoxymethylsilyl)-1-propanol in novel applications, including its use in drug delivery systems and as a precursor for advanced materials. Scientists are exploring how this compound can enhance the bioavailability of therapeutic agents or improve the performance of biomaterials.

In summary, 3-(dimethoxymethylsilyl)-1-propanol is a versatile organosilicon compound with significant applications in coatings, adhesives, silicone elastomers, and modified silica materials. Its unique chemical properties enable it to serve as a valuable component in various formulations, contributing to improved performance and durability. Ongoing research may uncover additional applications, solidifying its role in the chemical industry.