Nerol
[CAS# 106-25-2]

Identification

• Classification: Flavors and spices >> Synthetic spice >> Alcoholic spice >> Terpene alcohol
• Name: Nerol
• Synonyms: (2Z)-3,7-dimethyl-2,6-octadien-1-ol
• Molecular Formula: C₁₀H₁₈O
• Molecular Weight: 154.25
• CAS Registry Number: 106-25-2
• EC Number: 203-378-7
• FEMA: 2770
• SMILES: CC(=CCC/C(=C\CO)/C)C

Properties

• Density: 0.87 g/mL
• Boiling point: 227 ºC
• Refractive index: 1.467-1.478
• Flash point: 77 ºC

Safety Data

• Hazard Symbols: GHS05;GHS07 Danger
• Hazard Statements: H315-H317-H318-H319
• Precautionary Statements: P261-P264-P264+P265-P272-P280-P302+P352-P305+P351+P338-P305+P354+P338-P317-P321-P332+P317-P333+P317-P337+P317-P362+P364-P501

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Skin irritation	Skin Irrit.	2	H315
Skin sensitization	Skin Sens.	1B	H317
Serious eye damage	Eye Dam.	1	H318
Eye irritation	Eye Irrit.	2	H319
Skin sensitization	Skin Sens.	1	H317
Specific target organ toxicity - single exposure	STOT SE	3	H335
Acute hazardous to the aquatic environment	Aquatic Acute	1	H400
Chronic hazardous to the aquatic environment	Aquatic Chronic	3	H412
Eye irritation	Eye Irrit.	2A	H319

Discovory and Applicatios

Nerol, a monoterpene alcohol, was first discovered in the early 19th century by the French chemist Joseph Nicolas Savory. It was isolated from the essential oils of various aromatic plants, including neroli, rose, and citronella. Savory's work contributed to the understanding of the chemical composition of essential oils and the identification of their key components. Nerol's distinct floral aroma and therapeutic properties sparked interest in its potential applications in perfumery, medicine, and other industries.

Nerol is highly valued in perfumery for its delicate floral scent, reminiscent of roses and citrus blossoms. It is widely used in perfumes, colognes, and fragrances for its sweet and uplifting aroma. Nerol adds a fresh and feminine character to fragrances, often serving as a top or middle note. Its versatility allows it to blend harmoniously with other floral, fruity, and woody notes, contributing to the complexity and elegance of perfumes.

In the food and beverage industry, nerol is used as a flavoring agent and natural additive. Its floral and citrusy notes enhance the taste of various products, including desserts, beverages, and confectionery. Nerol is commonly found in rose-flavored foods and drinks, providing a subtle and aromatic taste. It is also used in herbal teas and aromatics, adding a refreshing and floral touch.

Nerol is prized in aromatherapy for its therapeutic properties and mood-enhancing effects. It is known for its calming and relaxing properties, making it beneficial for reducing stress, anxiety, and tension. Nerol essential oil is diffused or used in massage blends to create a soothing atmosphere and promote emotional well-being. Its floral aroma is comforting and uplifting, making it a popular choice for aromatherapy practitioners and enthusiasts.

Nerol is used in cosmetics and personal care products for its fragrance and skin-conditioning properties. It is added to lotions, creams, and skincare formulations for its aromatic benefits and moisturizing effects. Nerol helps to enhance the scent of products while providing additional benefits for the skin. Its soothing and hydrating properties make it suitable for various skincare applications, promoting soft and supple skin.

Nerol exhibits potential pharmacological properties, including antimicrobial, antioxidant, and anti-inflammatory effects. It is being studied for its therapeutic potential in various medicinal applications, including herbal medicine and traditional remedies. Nerol may have applications in treating skin conditions, respiratory ailments, and inflammatory disorders. Research is ongoing to explore its efficacy and safety in pharmaceutical formulations and herbal remedies.

References

2025. Antimicrobial activity of essential oil components against Escherichia coli depends on the food components present in a food matrix. Food Microbiology, 126.
DOI: 10.1016/j.fm.2024.104638

2008. Wine flavor: chemistry in a glass. Chemical Society Reviews, 37(12).
DOI: 10.1039/b714455p

2015. Terpene cyclization catalysed inside a self-assembled cavity. Nature Chemistry, 7(6).
DOI: 10.1038/nchem.2181