Endoxifen
[CAS# 112093-28-4]

Identification

• Classification: API >> Antineoplastic agents
• Name: Endoxifen
• Synonyms: 4-[(1Z)-1-[4-[2-(Methylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenol; 4-Hydroxy-N-desmethyltamoxifen; N-Desmethyl-4-hydroxytamoxifen
• Molecular Formula: C₂₅H₂₇NO₂
• Molecular Weight: 373.49
• CAS Registry Number: 112093-28-4
• EC Number: 683-027-6

Properties

• Solubility: Practically insoluble (0.013 g/L) (25 ºC), Calc.^*
• Density: 1.099±0.06 g/cm³ (20 ºC 760 Torr), Calc.^*
• Melting point: 139-143 ºC^**

^* Calculated using Advanced Chemistry Development (ACD/Labs) Software V11.02 (©1994-2016 ACD/Labs)

^** Ali, Shoukath M.; Bioorganic & Medicinal Chemistry Letters 2010, V20(8), P2665-2667.

Safety Data

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Acute hazardous to the aquatic environment	Aquatic Acute	1	H400
Eye irritation	Eye Irrit.	2A	H319
Specific target organ toxicity - single exposure	STOT SE	3	H335
Skin irritation	Skin Irrit.	2	H315