Sodium bicarbonate
[CAS# 144-55-8]

Identification

• Classification: API >> Digestive system medication >> Acid and gastric mucosal protective drugs
• Name: Sodium bicarbonate
• Synonyms: Sodium hydrogen carbonate; Sodium hydrocarbonate
• Molecular Formula: NaHCO₃
• Molecular Weight: 84.01
• CAS Registry Number: 144-55-8
• EC Number: 205-633-8
• SMILES: C(=O)(O)[O-].[Na+]

Properties

• Density: 2.159 g/mL (Expl.)
• Melting point: 300 ºC (Expl.)
• Refraction index: 1.5 (Expl.)
• Boiling point: 851 ºC (Expl.)
• Water solubility: 9 g/100 mL (20 ºC) (Expl.)

Safety Data

• Safety Description: S24/25

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Eye irritation	Eye Irrit.	2	H319
Skin irritation	Skin Irrit.	2	H315
Specific target organ toxicity - single exposure	STOT SE	3	H335
Acute toxicity	Acute Tox.	4	H332
Eye irritation	Eye Irrit.	2A	H319
Serious eye damage	Eye Dam.	1	H318

Discovory and Applicatios

Sodium bicarbonate, commonly known as baking soda, is a white, crystalline powder that has a wide range of applications in various industries. It is chemically represented as NaHCO₃ and is widely known for its use as a leavening agent in baking, but its utility extends far beyond the kitchen. Sodium bicarbonate was first discovered in the 19th century and has since become one of the most widely used chemicals globally. Its applications include use in cleaning, medicine, personal care, and even as an important component in fire extinguishers, among other fields.

The discovery of sodium bicarbonate is attributed to the work of early chemists studying natural minerals. Sodium bicarbonate is found in nature in the form of the mineral nahcolite, which was first discovered in Colorado in the 19th century. However, it was not until the 1840s that the production of sodium bicarbonate became a commercial process. The Solvay process, developed by Belgian chemist Ernest Solvay in the 1860s, was a breakthrough in industrial chemistry and allowed for the mass production of sodium bicarbonate. This process uses sodium chloride (table salt), limestone, and ammonia to produce sodium bicarbonate on a large scale. The discovery and industrialization of sodium bicarbonate opened the door to its wide range of applications.

One of the most common uses of sodium bicarbonate is in baking. As a leavening agent, it reacts with acidic ingredients such as vinegar, lemon juice, or buttermilk to release carbon dioxide gas. This gas causes dough and batter to rise, giving baked goods a light and fluffy texture. Sodium bicarbonate is often combined with an acid in recipes for cakes, cookies, and breads, making it an indispensable ingredient in the food industry.

Beyond the kitchen, sodium bicarbonate has a broad range of other applications. In the household, it is commonly used as a cleaning agent. Its mild abrasive properties make it effective in scrubbing surfaces without scratching them, and its ability to neutralize odors makes it a popular choice for deodorizing refrigerators, carpets, and other spaces. Sodium bicarbonate is also used in laundry detergents, where it helps to soften water and enhance the cleaning power of the detergent.

In the medical field, sodium bicarbonate is used as an antacid to treat heartburn and indigestion. It works by neutralizing excess stomach acid, providing relief from symptoms of acid reflux. Sodium bicarbonate is also used in emergency medicine, particularly in the treatment of metabolic acidosis, a condition in which the body produces too much acid. It is administered intravenously to help restore the body’s pH balance in such cases. Additionally, sodium bicarbonate is used in certain medical tests, such as the measurement of gastric acid secretion.

In personal care products, sodium bicarbonate is often found in toothpaste, where it acts as a mild abrasive to remove plaque and stains from teeth. It is also used in deodorants and bath products due to its odor-neutralizing properties. Sodium bicarbonate's gentle, non-toxic nature makes it suitable for a wide range of personal care applications, including as a gentle exfoliant in skincare products.

Sodium bicarbonate also plays an important role in fire safety. It is a key ingredient in certain types of fire extinguishers, particularly those used for electrical or grease fires. When sodium bicarbonate is heated, it releases carbon dioxide gas, which helps to suffocate flames. This property makes it a valuable component in both commercial and residential fire safety equipment.

In the agriculture industry, sodium bicarbonate is used as a fungicide and pesticide. It can be applied to crops to control fungal diseases, particularly those caused by molds and mildew. Its relatively low toxicity and effectiveness make it an attractive alternative to harsher chemical treatments in organic farming.

Despite its widespread use, sodium bicarbonate must be handled with care in some industrial applications, particularly in large-scale manufacturing processes. In high concentrations, it can pose a risk of inhalation or skin irritation, and exposure to concentrated sodium bicarbonate solutions should be avoided. However, for most everyday uses, sodium bicarbonate is considered safe and non-toxic.

In conclusion, sodium bicarbonate is a versatile and widely used compound that has many important applications across various industries. From baking and cleaning to medicine and fire safety, its discovery and widespread use have made it an essential chemical in everyday life. As research continues to explore its potential applications, sodium bicarbonate will likely remain a key chemical compound with numerous uses.

References

2015-05-11. Bicarbonate and cytoplasmic pH
DOI: 10.1016/0140-6736(90)91911-s

1990-05. Mitochondrial respiration in myocardial biopsy samples as a criterion of postischemic recovery of the cardiac contractility
DOI: 10.1007/bf01907119

1979-06-25. Microcalorimetric investigations of the metabolism of isolated human epidermis
DOI: 10.1007/bf00407882