4-(6-Fluoropyridin-3-yl)-6-(2-hydroxy-2-methylpropoxy)pyrazolo[1,5-a]pyridine-3-carbonitrile
[CAS# 2222653-74-7]

Identification

• Classification: API >> Antineoplastic agents
• Name: 4-(6-Fluoropyridin-3-yl)-6-(2-hydroxy-2-methylpropoxy)pyrazolo[1,5-a]pyridine-3-carbonitrile
• Molecular Formula: C₁₇H₁₅FN₄O₂
• Molecular Weight: 326.33
• CAS Registry Number: 2222653-74-7
• SMILES: CC(C)(COC1=CN2C(=C(C=N2)C#N)C(=C1)C3=CN=C(C=C3)F)O

Properties

• Density: 1.3±0.1 g/cm³, Calc.^*
• Index of Refraction: 1.623, Calc.^*

^* Calculated using Advanced Chemistry Development (ACD/Labs) Software.

Safety Data

• Hazard Symbols: GHS07 Warning
• Hazard Statements: H302-H315-H319-H335
• Precautionary Statements: P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501

Discovory and Applicatios

The chemical compound 4-(6-Fluoropyridin-3-yl)-6-(2-hydroxy-2-methylpropoxy)pyrazolo[1,5-a]pyridine-3-carbonitrile, known for its complex structure and unique properties, was discovered during a research initiative aimed at developing new pharmaceutical agents with potential applications in treating various diseases. The synthesis of this compound involved innovative methods combining pyrazolo[1,5-a]pyridine and fluoropyridine derivatives, leading to a molecule with significant biological activity. This discovery is part of a broader effort to identify and develop novel compounds with specific therapeutic targets, highlighting the advancements in medicinal chemistry and the ongoing quest to address unmet medical needs.

The applications of 4-(6-Fluoropyridin-3-yl)-6-(2-hydroxy-2-methylpropoxy)pyrazolo[1,5-a]pyridine-3-carbonitrile span various fields, primarily focusing on its potential in pharmaceutical development. Its unique structure suggests it can act as a potent inhibitor in specific biological pathways, making it a promising candidate for drug development. One significant application lies in oncology, where it can target and inhibit enzymes crucial for cancer cell proliferation. By interfering with these enzymes, the compound can potentially slow down or halt the progression of certain cancers, offering a new avenue for treatment.

Moreover, this compound may exhibit anti-inflammatory properties, providing relief for chronic inflammatory conditions such as rheumatoid arthritis. By modulating the inflammatory response, it can help reduce symptoms and improve the quality of life for patients suffering from such conditions. This anti-inflammatory action can also extend to neuroinflammatory disorders, where controlling inflammation is crucial for managing diseases like multiple sclerosis and Alzheimer's.

In addition to its therapeutic potential, 4-(6-Fluoropyridin-3-yl)-6-(2-hydroxy-2-methylpropoxy)pyrazolo[1,5-a]pyridine-3-carbonitrile could be valuable in research settings. It can serve as a tool for studying biological processes and disease mechanisms, helping scientists understand how certain pathways function and how they can be manipulated for therapeutic benefit. This research can pave the way for discovering new targets and developing additional compounds with improved efficacy and safety profiles.

Furthermore, its chemical properties might be utilized in designing new drug delivery systems. The compound's stability and ability to interact with specific biological targets can be harnessed to develop targeted delivery mechanisms, ensuring that therapeutic agents are delivered directly to the affected areas, thereby increasing their effectiveness and minimizing side effects.