4-(6-Fluoropyridin-3-yl)-6-hydroxypyrazolo[1,5-a]pyridine-3-carbonitrile
[CAS# 2222654-09-1]

Identification

• Classification: API >> Antineoplastic agents
• Name: 4-(6-Fluoropyridin-3-yl)-6-hydroxypyrazolo[1,5-a]pyridine-3-carbonitrile
• Molecular Formula: C₁₃H₇FN₄O
• Molecular Weight: 254.22
• CAS Registry Number: 2222654-09-1
• SMILES: C1=CC(=NC=C1C2=CC(=CN3C2=C(C=N3)C#N)O)F

Discovory and Applicatios

The chemical compound 4-(6-Fluoropyridin-3-yl)-6-hydroxypyrazolo[1,5-a]pyridine-3-carbonitrile was discovered through focused research efforts aimed at finding new molecules with potential therapeutic benefits. This compound is a product of intricate synthetic processes involving the fusion of fluoropyridine and pyrazolo[1,5-a]pyridine frameworks. Researchers identified this molecule while exploring derivatives with significant biological activity, particularly in targeting specific enzymes and receptors. The discovery marks a significant step in medicinal chemistry, providing a new scaffold for developing drugs aimed at treating a range of diseases.

The compound 4-(6-Fluoropyridin-3-yl)-6-hydroxypyrazolo[1,5-a]pyridine-3-carbonitrile holds considerable promise in various pharmaceutical applications. One of its primary potential uses is in the field of oncology. The unique structure of this compound allows it to inhibit specific enzymes involved in cancer cell proliferation and survival. By targeting these enzymes, the compound can disrupt cancer cell growth and induce apoptosis, making it a valuable candidate for developing new anticancer therapies. Its efficacy in preclinical studies suggests that it could be instrumental in treating various types of cancer, either as a standalone treatment or in combination with other therapies.

Another significant application is in the treatment of inflammatory diseases. The compound's ability to modulate inflammatory pathways makes it a promising candidate for addressing conditions such as rheumatoid arthritis and inflammatory bowel disease. By inhibiting key enzymes in the inflammatory response, it can help reduce inflammation and alleviate symptoms, improving patients' quality of life. This anti-inflammatory property also opens up possibilities for treating neuroinflammatory disorders, where managing inflammation is crucial for preventing neuronal damage and disease progression.

Additionally, 4-(6-Fluoropyridin-3-yl)-6-hydroxypyrazolo[1,5-a]pyridine-3-carbonitrile could serve as a valuable tool in biomedical research. It can be used to study the mechanisms of enzyme inhibition and the effects of enzyme modulation on various biological processes. This research can further our understanding of disease mechanisms and aid in the identification of new therapeutic targets.

Furthermore, the compound's chemical characteristics might be exploited in the design of targeted drug delivery systems. Its stability and specificity for certain biological targets can be utilized to develop delivery mechanisms that direct therapeutic agents precisely to disease sites, enhancing treatment efficacy and reducing side effects.