VH032-cyclopropane-F
[CAS# 2306193-99-5]

Identification

• Classification: Organic raw materials >> Heterocyclic compound >> Pyrroles
• Name: VH032-cyclopropane-F
• Synonyms: N-[(1-Fluorocyclopropyl)carbonyl]-3-methyl-L-valyl-(4R)-4-hydroxy-N-[2-hydroxy-4-(4-methyl-1,3-thiazol-5-yl)benzyl]-L-prolinamide; (2S,4R)-1-[(2S)-2-[(1-fluorocyclopropanecarbonyl)amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[2-hydroxy-4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide
• Molecular Formula: C₂₆H₃₃FN₄O₅S
• Molecular Weight: 532.63
• CAS Registry Number: 2306193-99-5
• SMILES: CC1=C(SC=N1)C2=CC(=C(C=C2)CNC(=O)[C@@H]3C[C@H](CN3C(=O)[C@H](C(C)(C)C)NC(=O)C4(CC4)F)O)O

Properties

• Density: 1.4±0.1 g/cm³, Calc.^*
• Index of Refraction: 1.629, Calc.^*
• Boiling Point: 841.7±65.0 ºC (760 mmHg), Calc.^*
• Flash Point: 462.9±34.3 ºC, Calc.^*

^* Calculated using Advanced Chemistry Development (ACD/Labs) Software.

Safety Data

• Hazard Symbols: GHS07 Warning
• Hazard Statements: H315-H319-H335
• Precautionary Statements: P261-P264-P271-P280-P302+P352-P304+P340+P312-P305+P351+P338-P332+P313-P337+P313-P362-P403+P233-P405-P501

Discovory and Applicatios

In the realm of chemical innovation, VH032-cyclopropane-F stands as a testament to human ingenuity and scientific progress. This extraordinary substance, discovered at the intersection of chemistry and medicine, has generated great excitement and holds great promise for a wide range of applications. The discovery of VH032-cyclopropane-F stems from intensive research aimed at manipulating cellular processes by chemical means. Its synthesis, developed by a team of pioneering chemists and biologists, represents a major leap forward in targeted pharmacology. The unique structure of the compound, incorporating the cyclopropane-F moiety, enhances its biological activity and specificity, setting it apart from conventional compounds.

In essence, VH032-cyclopropane-F works by selectively inhibiting specific protein-protein interactions that are critical in cell signaling pathways. This precise mode of action provides researchers with unprecedented control over cellular function, opening the way for novel therapeutic interventions. By disrupting key interactions implicated in disease progression, such as cancer and inflammatory diseases, VH032-cyclopropane-F is expected to become a powerful tool in the fight against complex diseases.

The medical implications of VH032-cyclopropane-F are enormous and transformative. Initial studies have highlighted its potential in cancer treatment, where it is expected to inhibit oncogenic pathways without the broad cytotoxic effects of traditional chemotherapy. In addition, its ability to modulate immune responses makes it a potential candidate for the treatment of autoimmune diseases, offering hope for more targeted and effective treatments.

The journey of VH032-cyclopropane-F is filled with promise and challenges. Ongoing research aims to optimize its pharmacokinetics and expand its use across a range of diseases. Challenges include scalability of synthesis, ensuring safety, and finding regulatory pathways for clinical translation.