N-[3-(Dimethylamino)propyl]urea
[CAS# 31506-43-1]

Identification

• Classification: Chemical reagent >> Organic reagent >> Urea
• Name: N-[3-(Dimethylamino)propyl]urea
• Synonyms: [3-(Dimethylamino)propyl]urea
• Molecular Formula: C₆H₁₅N₃O
• Molecular Weight: 145.20
• CAS Registry Number: 31506-43-1
• EC Number: 401-950-2
• SMILES: CN(C)CCCNC(=O)N

Properties

• Solubility: Soluble (45 g/L) (25 ºC), Calc.^*
• Density: 1.005±0.06 g/cm³ (20 ºC 760 Torr), Calc.^*
• Boiling point: 224.4±32.0 ºC (760 Torr), Calc.^*
• Flash point: 89.5±25.1 ºC, Calc.^*

^* Calculated using Advanced Chemistry Development (ACD/Labs) Software V11.02 (©1994-2013 ACD/Labs)

Safety Data

• Hazard Symbols: GHS05 Danger
• Hazard Statements: H318
• Precautionary Statements: P264+P265-P280-P305+P354+P338-P317

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Serious eye damage	Eye Dam.	1	H318

Discovory and Applicatios

N-[3-(Dimethylamino)propyl]urea is an organic compound characterized by its urea functional group and a dimethylamino substituent. Its discovery is linked to ongoing research in medicinal chemistry and drug development, particularly in the design of compounds with potential therapeutic applications. The structure of N-[3-(Dimethylamino)propyl]urea enables it to engage in hydrogen bonding and other interactions, which are critical for biological activity.

The synthesis of N-[3-(Dimethylamino)propyl]urea typically involves the reaction of 3-(dimethylamino)propylamine with a suitable carbonyl compound, such as phosgene or isocyanates. This reaction leads to the formation of the urea linkage, a process that is both efficient and effective in producing the desired compound. The development of this compound has been of particular interest to researchers investigating its pharmacological properties.

One of the most notable applications of N-[3-(Dimethylamino)propyl]urea is in the field of medicinal chemistry, where it has been studied for its potential as a therapeutic agent. The compound has been explored for its ability to interact with various biological targets, including receptors and enzymes. Research has shown that N-[3-(Dimethylamino)propyl]urea can exhibit anticonvulsant properties, making it a candidate for further investigation in the treatment of neurological disorders. Its mechanism of action involves modulation of neurotransmitter systems, which can be crucial in managing conditions such as epilepsy.

Additionally, N-[3-(Dimethylamino)propyl]urea has been utilized in the development of surfactants and emulsifiers. The presence of the dimethylamino group imparts surfactant properties to the compound, making it suitable for applications in formulations where stabilization of emulsions is essential. This is particularly relevant in the cosmetic and pharmaceutical industries, where the formulation of creams, lotions, and ointments often requires effective emulsifying agents to ensure product stability and performance.

In the agricultural sector, N-[3-(Dimethylamino)propyl]urea has shown potential as a plant growth regulator. Compounds with similar structures have been investigated for their ability to influence plant growth and development by modulating hormonal pathways. This application could provide valuable tools for enhancing crop yield and resilience in various agricultural systems.

Despite its promising applications, safety and regulatory considerations are paramount in the use of N-[3-(Dimethylamino)propyl]urea. Comprehensive studies are essential to assess the compound’s toxicity and environmental impact. Regulatory agencies evaluate such compounds to ensure they meet safety standards before being approved for commercial use.

In conclusion, N-[3-(Dimethylamino)propyl]urea is a versatile organic compound with applications spanning medicinal chemistry, surfactant formulation, and agricultural use. Its unique chemical structure allows for a variety of interactions that are critical for its biological activity and practical applications. As research continues to explore the potential of this compound, N-[3-(Dimethylamino)propyl]urea is positioned to contribute significantly to advancements in multiple fields.