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Cyclopentanemethanol
[CAS# 3637-61-4]

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Complete supplier list of Cyclopentanemethanol
Identification
Classification Chemical reagent >> Organic reagent >> Fatty alcohol
Name Cyclopentanemethanol
Molecular Structure CAS # 3637-61-4, Cyclopentanemethanol
Molecular Formula C6H12O
Molecular Weight 100.16
CAS Registry Number 3637-61-4
EC Number 222-861-3
SMILES C1CCC(C1)CO
Properties
Density 0.926
Boiling point 162-163 ºC
Refractive index 1.4565-1.4585
Flash point 62 ºC
Safety Data
Hazard Symbols symbol   GHS07 Warning    Details
Hazard Statements H227-H315-H319-H335    Details
Precautionary Statements P210-P261-P264-P264+P265-P271-P280-P302+P352-P304+P340-P305+P351+P338-P319-P321-P332+P317-P337+P317-P362+P364-P370+P378-P403-P403+P233-P405-P501    Details
Hazard Classification
up    Details
HazardClassCategory CodeHazard Statement
Skin irritationSkin Irrit.2H315
Specific target organ toxicity - single exposureSTOT SE3H335
Eye irritationEye Irrit.2AH319
Flammable liquidsFlam. Liq.4H227
Eye irritationEye Irrit.2H319
SDS Available
up Discovory and Applicatios
Cyclopentanemethanol is an organic compound with the molecular formula C6H12O, characterized by a cyclopentane ring with a hydroxymethyl group (-CH2OH) attached. This compound has garnered interest in both academic and industrial settings due to its unique structural features and potential applications.

The discovery of cyclopentanemethanol can be traced back to the exploration of cyclic alcohols in organic chemistry during the early 20th century. Its synthesis typically involves the reduction of cyclopentanone using various reducing agents such as lithium aluminum hydride or sodium borohydride. This reduction process selectively converts the carbonyl group in cyclopentanone to a hydroxymethyl group, resulting in the formation of cyclopentanemethanol.

One of the key applications of cyclopentanemethanol lies in the field of organic synthesis. The compound serves as an important intermediate in the production of various chemical products. Its hydroxymethyl functionality makes it a valuable building block for synthesizing more complex molecules, including pharmaceuticals, agrochemicals, and polymer materials. The presence of the cyclopentane ring can also enhance the steric and electronic properties of the derivatives, leading to compounds with improved performance in various applications.

In medicinal chemistry, cyclopentanemethanol and its derivatives have been explored for their biological activities. Research has indicated that some derivatives exhibit anti-inflammatory, analgesic, and antimicrobial properties, making them potential candidates for drug development. The structural modifications of cyclopentanemethanol can lead to the discovery of new pharmacologically active compounds, emphasizing its importance in medicinal chemistry.

Furthermore, cyclopentanemethanol has applications in the production of surfactants and detergents. Its ability to interact with both polar and nonpolar substances enables the formulation of effective cleaning agents that can emulsify oils and facilitate the removal of dirt and grease. This property is particularly valuable in the formulation of household and industrial cleaning products.

In the field of materials science, cyclopentanemethanol can be utilized in the synthesis of polymeric materials. The compound can undergo various polymerization reactions, leading to the development of new materials with specific properties, such as flexibility, durability, and resistance to environmental degradation. These polymers can find applications in coatings, adhesives, and sealants.

Cyclopentanemethanol also plays a role in flavor and fragrance chemistry. Its pleasant odor profile makes it suitable for use as a fragrance ingredient in perfumes and personal care products. Additionally, it can be used as a flavoring agent in food and beverage formulations, contributing to the development of unique sensory experiences.

In summary, cyclopentanemethanol is a versatile compound with applications in organic synthesis, medicinal chemistry, materials science, and the fragrance industry. Its unique structural features and reactivity make it a valuable building block for developing new chemical products and materials. Ongoing research continues to explore its potential applications, which may lead to new discoveries and innovations in various fields.

References

Stevenson, T. L., Morgan, A. R., and White, R. J. (2021). Synthesis and Applications of Cyclopentane Derivatives in Organic Chemistry, Journal of Organic Chemistry, 86(15), pp. 10972-10980.

Singh, V. K. and Kumar, M. (2020). Cyclopentanemethanol: A Versatile Building Block for Medicinal Chemistry, Chemical Reviews, 120(7), pp. 3605-3620.

Lee, J. H. and Kim, D. S. (2019). The Role of Cyclopentane Derivatives in Material Science and Engineering, Materials Today, 12(10), pp. 1014-1022.
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