Doxylamine
[CAS# 469-21-6]

Identification

• Classification: API >> Antiallergic >> Antihistamine
• Name: Doxylamine
• Synonyms: (±)-Doxylamine; 2-[alpha-[2-(Dimethylamino)ethoxy]-alpha-methylbenzyl]pyridine
• Molecular Formula: C₁₇H₂₂N₂O
• Molecular Weight: 270.37
• CAS Registry Number: 469-21-6
• EC Number: 207-414-2

Properties

• Solubility: Slightly soluble (2.5 g/L) (25 ºC), Calc.^*
• Density: 1.043±0.06 g/cm³ (20 ºC 760 Torr), Calc.^*
• Melting point: <25 ºC^**
• Refractive index: 1.5804 (589.3 nm 20 ºC)^***

^* Calculated using Advanced Chemistry Development (ACD/Labs) Software V11.02 (©1994-2015 ACD/Labs)

^** "PhysProp" data were obtained from Syracuse Research Corporation of Syracuse, New York (US)

^*** Tilford, Charles H.; Journal of the American Chemical Society 1948, V70, P4001-9.

Safety Data

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Acute toxicity	Acute Tox.	4	H302
Eye irritation	Eye Irrit.	2	H319
Chronic hazardous to the aquatic environment	Aquatic Chronic	3	H412
Specific target organ toxicity - single exposure	STOT SE	3	H335
Skin irritation	Skin Irrit.	2	H315