Chloramphenicol
[CAS# 56-75-7]

Identification

• Classification: API >> Antibiotics >> Amide alcohol
• Name: Chloramphenicol
• Synonyms: 2,2-Dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide; D-(-)-threo-2,2-Dichloro-N-[beta-hydroxy-alpha-(hydroxy-methyl)-p-nitrophenethyl]acetamide; Chloromycetin
• Molecular Formula: C₁₁H₁₂Cl₂N₂O₅
• Molecular Weight: 323.13
• CAS Registry Number: 56-75-7
• EC Number: 200-287-4

Properties

• Melting point: 149-153 ºC
• alpha: 19.5 º (c=6, EtOH)
• Water solubility: 2.5 g/L (25 º C)

Safety Data

• Hazard Symbols: T
• Risk Codes: R45
• Safety Description: S45;S53

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Carcinogenicity	Carc.	1B	H350
Reproductive toxicity	Repr.	2	H361
Carcinogenicity	Carc.	1A	H350
Carcinogenicity	Carc.	2	H351
Skin sensitization	Skin Sens.	1	H317
Reproductive toxicity	Repr.	1B	H360
Serious eye damage	Eye Dam.	1	H318
Germ cell mutagenicity	Muta.	1B	H340
Reproductive toxicity	Lact.	-	H362
Specific target organ toxicity - repeated exposure	STOT RE	2	H373
Respiratory sensitization	Resp. Sens.	1	H334
Germ cell mutagenicity	Muta.	2	H341
Acute hazardous to the aquatic environment	Aquatic Acute	1	H400
Acute toxicity	Acute Tox.	4	H302
Specific target organ toxicity - repeated exposure	STOT RE	1	H372
Specific target organ toxicity - single exposure	STOT SE	2	H371
Skin irritation	Skin Irrit.	2	H315
Reproductive toxicity	Repr.	2	H361fd
Reproductive toxicity	Repr.	2	H361d
Specific target organ toxicity - single exposure	STOT SE	1	H370
Skin corrosion	Skin Corr.	1A	H314

• Transport Information: UN 1851