Pacritinib
[CAS# 937272-79-2]

Identification

• Classification: Biochemical >> Inhibitor >> Tyrosine protein kinase/signal transducer and transcriptional activator inhibitor (JAK/STAT) >> JAK inhibitor
• Name: Pacritinib
• Synonyms: (16E)-11-[2-(1-Pyrrolidinyl)ethoxy]-14,19-dioxa-5,7,27-triazatetracyclo[19.3.1.1(2,6).1(8,12)]heptacosa-1(25),2,4,6(27),8,10,12(26),16,21,23-decaene
• Molecular Formula: C₂₈H₃₂N₄O₃
• Molecular Weight: 472.58
• CAS Registry Number: 937272-79-2
• EC Number: 812-740-9

Properties

• Solubility: Insoluble (2.3E^-3 g/L) (25 ºC), Calc.^*
• Density: 1.22±0.1 g/cm³ (20 ºC 760 Torr), Calc.^*

^* Calculated using Advanced Chemistry Development (ACD/Labs) Software V11.02 (©1994-2014 ACD/Labs)

Safety Data

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Specific target organ toxicity - repeated exposure	STOT RE	2	H373
Chronic hazardous to the aquatic environment	Aquatic Chronic	2	H411
Acute hazardous to the aquatic environment	Aquatic Acute	1	H400