Calcium levomefolate
[CAS# 151533-22-1]

Identification

• Classification: Organic raw materials >> Organometallic compound >> Organic calcium
• Name: Calcium levomefolate
• Synonyms: N-[4-[[(2-Amino-1,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid calcium salt
• Molecular Formula: C₂₀H₂₃CaN₇O₆
• Molecular Weight: 497.52
• CAS Registry Number: 151533-22-1
• EC Number: 691-636-3
• SMILES: CN1[C@H](CNC2=C1C(=O)NC(=N2)N)CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)[O-])C(=O)[O-].[Ca+2]

Safety Data

• Hazard Symbols: GHS07 Warning
• Hazard Statements: H302-H315-H319-H332-H335
• Precautionary Statements: 261-P280-P305+P351+P338

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Skin irritation	Skin Irrit.	2	H315
Acute toxicity	Acute Tox.	4	H302
Specific target organ toxicity - single exposure	STOT SE	3	H335
Eye irritation	Eye Irrit.	2	H319

Discovory and Applicatios

Calcium Levomethylfolate is a biologically active form of folate, the calcium salt of L-methylfolate. It is an essential compound in the fields of nutrition and medicine, notable for its role in various biological processes.

Calcium Levomethylfolate was born out of research into the role of folate in human health. Folate is a B vitamin that is essential for DNA synthesis, repair, and cellular function. Unlike folic acid, which is the synthetic form of folate, L-methylfolate is a naturally occurring, biologically active form that the body can use directly. The discovery and development of Calcium Levomethylfolate focused on providing a stable, bioavailable form of L-methylfolate. This compound was synthesized to enhance its stability and efficacy as a dietary supplement and therapeutic agent.

Calcium Levomethylfolate is widely used as a dietary supplement to address folate deficiency. It is particularly important for individuals who have difficulty converting folate to its active form due to genetic variations or health conditions. As a supplement, it supports various physiological functions, including cell division and the production of red blood cells.

During pregnancy, adequate folate intake is essential for fetal development, especially in preventing neural tube defects. Levomethylfolate calcium is used in prenatal vitamins to ensure pregnant women receive adequate levels of active folate, which is essential for healthy fetal growth and development.

Research suggests that levomethylfolate calcium may have potential benefits for mental health. It is being studied for its role in treating mood disorders such as depression, especially in individuals with genetic mutations that affect folate metabolism. The compound's ability to cross the blood-brain barrier and affect neurotransmitter function makes it a hot topic in psychiatric research.

Elevated homocysteine ​​levels are associated with cardiovascular disease. Levomethylfolate calcium may help regulate homocysteine ​​levels by supporting its metabolism. This application is beneficial for individuals who have elevated homocysteine ​​levels and may not be able to metabolize folate effectively.