Clotiapine
[CAS# 2058-52-8]

Identification

• Classification: API >> Nervous system medication >> Antipsychotic
• Name: Clotiapine
• Synonyms: 2-Chloro-11-(4-methylpiperazino)dibenzo[b,f][1,4]thiazepine; Clothiapin; Clothiapine; Clotiapine; Deliton; Entumine; Etumine; HF 2159; LW 2159
• Molecular Formula: C₁₈H₁₈ClN₃S
• Molecular Weight: 343.87
• CAS Registry Number: 2058-52-8
• EC Number: 218-162-8

Properties

• Solubility: Insoluble (2.2E^-3 g/L) (25 ºC), Calc.^*
• Density: 1.33±0.1 g/cm³ (20 ºC 760 Torr), Calc.^*
• Melting point: 121-123 ºC^**

^* Calculated using Advanced Chemistry Development (ACD/Labs) Software V11.02 (©1994-2014 ACD/Labs)

^** Schmutz, Jean; Helvetica Chimica Acta 1967, V50(1), P245-54.

Safety Data

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Chronic hazardous to the aquatic environment	Aquatic Chronic	1	H410
Acute hazardous to the aquatic environment	Aquatic Acute	1	H400
Acute toxicity	Acute Tox.	3	H301
Acute toxicity	Acute Tox.	4	H302
Acute toxicity	Acute Tox.	4	H332