TrixiePhos Pd G3
[CAS# 2230788-63-1]

Identification

• Classification: Organic raw materials >> Organometallic compound >> Organic palladium
• Name: TrixiePhos Pd G3
• Synonyms: Mesyl(2-(di-tert-butylphosphino)-1,1'-binaphthyl)[2-(2'-amino-1,1'-biphenyl)]palladium(II)
• Molecular Formula: C₄₁H₄₄NO₃PPdS
• Molecular Weight: 768.25
• CAS Registry Number: 2230788-63-1
• SMILES: NC1=C(C=CC=C1)C2=C([Pd]OS(C)(=O)=O)C=CC=C2.CC(C)(C)P(C3=CC=C4C(C=CC=C4)=C3C5=CC=CC6=C5C=CC=C6)C(C)(C)C

Properties

• Melting Point: 150-155 ºC (decomp.)

Safety Data

• Hazard Symbols: GHS07 Warning
• Hazard Statements: H302-H312-H332
• Precautionary Statements: P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P330-P363-P501

Discovory and Applicatios

TrixiePhos Pd G3 is a significant chemical compound in the field of catalysis, notable for its role as a palladium-based catalyst in various organic reactions. This complex features a palladium center coordinated with the TrixiePhos ligand, a highly specialized phosphine that enhances the catalyst's performance.

The discovery of TrixiePhos Pd G3 emerged from the need for more efficient and selective catalysts for complex organic transformations. The TrixiePhos ligand, distinguished by its unique structural features, was designed to optimize the stability and reactivity of palladium catalysts. The "G3" designation indicates that this is a third-generation variant, reflecting improvements in ligand design to boost catalytic efficiency and stability.

TrixiePhos Pd G3 is primarily utilized in cross-coupling reactions, such as the Suzuki-Miyaura and Heck reactions. These processes are crucial for forming carbon-carbon bonds, which are foundational in the synthesis of pharmaceuticals, agrochemicals, and advanced materials. The effectiveness of TrixiePhos Pd G3 in these reactions is due to the ligand’s ability to stabilize the palladium center and enhance the catalyst’s performance in terms of both selectivity and yield.

The third-generation design of TrixiePhos Pd G3 incorporates advancements that improve the catalyst's performance under a wider range of conditions and with greater tolerance to various functional groups. This results in more efficient reactions and higher product yields, making TrixiePhos Pd G3 a valuable tool for both academic research and industrial applications.

In addition to cross-coupling reactions, TrixiePhos Pd G3 is used in other palladium-catalyzed processes, including polymerizations and various coupling reactions. Its versatility and efficiency make it a preferred choice for researchers working on complex synthetic challenges.

Overall, TrixiePhos Pd G3 represents an important advancement in palladium-catalyzed chemistry. Its development has provided a robust catalyst for a range of organic reactions, contributing to advances in chemical synthesis and material science.