Hangzhou Verychem Science And Technology Co., Ltd. | China | Inquire | ||
---|---|---|---|---|
![]() |
+86 (571) 8816-2785 +86 13606544505 | |||
![]() |
lucy@verychem.com | |||
Chemical manufacturer since 2004 | ||||
chemBlink massive supplier since 2021 | ||||
Qingdao Free Trade Zone United International Co., Ltd. | China | Inquire | ||
---|---|---|---|---|
![]() |
+86 (532) 83893696 +86 13808950921 | |||
![]() |
jason.wang@unitedint.com | |||
![]() |
QQ chat | |||
Chemical distributor | ||||
chemBlink standard supplier since 2006 | ||||
Zhangjiagang Huachang Pharmaceutical Co., Ltd. | China | Inquire | ||
---|---|---|---|---|
![]() |
+86 (512) 5818-5820 +86 13812985197 | |||
![]() |
huachangpharm@163.com | |||
Chemical manufacturer | ||||
chemBlink standard supplier since 2007 | ||||
Simagchem Corporation | China | Inquire | ||
---|---|---|---|---|
![]() |
+86 13806087780 | |||
![]() |
sale@simagchem.com | |||
Chemical manufacturer since 2002 | ||||
chemBlink standard supplier since 2008 | ||||
Jiangsu B-Win Chemical Co., Ltd. | China | Inquire | ||
---|---|---|---|---|
![]() |
+86 (510) 8584-0252 +86 18861806888 | |||
![]() |
huisongshu_2001@163.com | |||
![]() |
QQ chat | |||
Chemical manufacturer | ||||
chemBlink standard supplier since 2008 | ||||
Extrasynthese Chemical S.A.S. | France | Inquire | ||
---|---|---|---|---|
![]() |
+33 (47) 898-2034 | |||
![]() |
info@extrasynthese.com | |||
Chemical manufacturer | ||||
chemBlink standard supplier since 2009 | ||||
Sinogel Amino Acid Co., Ltd. | China | Inquire | ||
---|---|---|---|---|
![]() |
+86 (551) 531-8010 523-2881 523-2882 | |||
![]() |
sales@sinogel.com sinogel@gmail.com | |||
Chemical manufacturer | ||||
chemBlink standard supplier since 2009 | ||||
Hefei TNJ Chemical Industry Co., Ltd. | China | Inquire | ||
---|---|---|---|---|
![]() |
+86 (551) 6541-8684 | |||
![]() |
sales@tnjchem.com | |||
Chemical manufacturer since 2001 | ||||
chemBlink standard supplier since 2010 | ||||
Classification | Organic raw materials >> Hydrocarbon compounds and their derivatives >> Hydrocarbon halide |
---|---|
Name | L-Alanine |
Synonyms | L-2-Aminopropanoic acid; Ala |
Molecular Structure | ![]() |
Protein Sequence | A |
Molecular Formula | C3H7NO2 |
Molecular Weight | 89.09 |
CAS Registry Number | 56-41-7 |
EC Number | 200-273-8 |
SMILES | C[C@@H](C(=O)O)N |
Melting point | 314-316 ºC |
---|---|
alpha | 14.5 º (c=10,6N HCl,dry sub.) |
Water solubility | 166.5 g/L (25 ºC) |
Hazard Symbols |
| ||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Hazard Statements | H315-H319-H335 Details | ||||||||||||||||||||||||
Precautionary Statements | P261-P305+P351+P338 Details | ||||||||||||||||||||||||
Hazard Classification | |||||||||||||||||||||||||
| |||||||||||||||||||||||||
SDS | Available | ||||||||||||||||||||||||
L-Alanine is one of the 20 standard α-amino acids commonly found in proteins. It has the chemical formula C3H7NO2 and a molecular structure consisting of a central α-carbon atom bonded to an amino group (–NH2), a carboxyl group (–COOH), a hydrogen atom, and a methyl side chain (–CH3). The methyl group makes alanine a nonpolar, aliphatic amino acid. L-Alanine is the naturally occurring enantiomer and is coded in proteins by the genetic codons GCU, GCC, GCA, and GCG. The discovery of alanine dates back to the 19th century. It was first isolated in the mid-1800s through the hydrolysis of proteinaceous materials. The name "alanine" is derived from the aldehyde "acetaldehyde," due to early hypotheses regarding its structure. It was among the early amino acids to be structurally characterized and studied for its role in protein composition. L-Alanine is a non-essential amino acid for humans, meaning that it can be synthesized by the body and does not need to be obtained through the diet. In animals, L-alanine is synthesized primarily from pyruvate by transamination reactions. The enzyme alanine aminotransferase (ALT) catalyzes the reversible conversion between pyruvate and L-alanine, using glutamate as the amino donor. This reaction is significant in nitrogen metabolism and is also a key part of the glucose-alanine cycle between muscle and liver. One of the important physiological roles of L-alanine is its function in the transport of amino groups and carbon skeletons in peripheral tissues to the liver, where gluconeogenesis occurs. In this process, muscle cells generate alanine by transferring amino groups to pyruvate; the alanine then travels through the bloodstream to the liver, where it is deaminated back to pyruvate for glucose production. This helps maintain blood glucose levels during periods of fasting or strenuous activity. L-Alanine is abundant in many proteins and tends to be found in α-helical regions due to its small side chain, which imposes minimal steric hindrance. Its nonpolar nature contributes to protein folding by stabilizing hydrophobic interactions in the interior of proteins. In structural biology, alanine scanning mutagenesis is often used to investigate the role of individual amino acids in proteins by systematically replacing them with alanine. Beyond its presence in proteins, L-alanine also finds application in food, pharmaceutical, and biochemical industries. It is used as a component of intravenous nutrition solutions, a flavor enhancer in food products due to its slightly sweet taste, and as a building block for the synthesis of peptides and other biomolecules. In biochemical assays, it is used as a standard amino acid for calibration and research. Clinically, alanine transaminase (ALT) activity in the blood is measured as a diagnostic marker for liver health. Elevated ALT levels are commonly associated with liver damage or inflammation, such as in hepatitis or drug-induced liver injury. In microbial metabolism, L-alanine is synthesized by bacteria and other microorganisms and incorporated into structural components such as peptidoglycan, particularly in Gram-positive bacteria, where D-alanine (produced from L-alanine by racemization) is used for cell wall cross-linking. In summary, L-alanine is a naturally occurring α-amino acid essential to protein structure and energy metabolism. It plays a vital role in glucose regulation, protein biosynthesis, and nitrogen transport, and is used in various scientific, medical, and industrial contexts. References 2025. Synthesis of Yellow Fluorescence Carbon Dots for the Applications of Vitamin B12 Detection and Cell Imaging. Journal of Fluorescence, 35(2). DOI: 10.1007/s10895-023-03558-9 2025. Alanine metabolism mediates energy allocation of the brown planthopper to adapt to resistant rice. Journal of Advanced Research, 55. DOI: 10.1016/j.jare.2024.01.022 2024. Chiral recognition of amino acids through homochiral metallacycle [ZnCl2L]2. Biomaterials Science, 12(24). DOI: 10.1039/d4bm01119h |
Market Analysis Reports |
List of Reports Available for L-Alanine |