Oxirane
[CAS# 75-21-8]

Identification

• Classification: Pharmaceutical intermediate >> Heterocyclic compound intermediate >> Pyrimidine compound >> Fluoropyrimidine
• Name: Oxirane
• Synonyms: 1,2-Epoxyethane; 12/88; Ciba-Geigy 9138; Dihydrooxirene; Dimethylene oxide; ETO; Epoxyethane; Ethene oxide; Mirror Ox; Oxacyclopropane; Oxane; Oxidoethane; Oxirene, dihydro-; Oxyfume; Oxyfume 12; Oxyfume 2002; T-Gas
• Molecular Formula: C₂H₄O
• Molecular Weight: 44.05
• CAS Registry Number: 75-21-8
• EC Number: 200-849-9

Properties

• Solubility: Soluble (69.6 g/L) (25 ºC), Calc.^*
• Density: 1.1238 g/cm³ (15 ºC)^**
• Melting point: 148.5-149.5 ºC^***
• Boiling point: 183-192 ºC (0.15 Torr)^****
• Refractive index: 1.4840 (589.3 nm 15 ºC)^**
• Flash point: -49.0±15.3 ºC, Calc.^*

^* Calculated using Advanced Chemistry Development (ACD/Labs) Software V11.02 (©1994-2014 ACD/Labs)

^** Ishii, Yoshio; Kogyo Kagaku Zasshi 1958, V61, P1254-7.

^*** Anon.; RD 465077 2003.

^**** Albrecht, Otto; CH 327517 1958.

Safety Data

• Hazard Symbols: GHS02;GHS05;GHS06;GHS08 Danger
• Hazard Statements: H220-H350-H340-H360Fd-H331-H301-H335-H336-H372

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Carcinogenicity	Carc.	1B	H350
Germ cell mutagenicity	Muta.	1B	H340
Specific target organ toxicity - single exposure	STOT SE	3	H335
Acute toxicity	Acute Tox.	3	H331
Gases under pressure (liquid)	Press. Gas (Liq.)		H280
Flammable gases	Flam. Gas	1	H220
Skin irritation	Skin Irrit.	2	H315
Specific target organ toxicity - repeated exposure	STOT RE	1	H372
Eye irritation	Eye Irrit.	2	H319
Acute toxicity	Acute Tox.	4	H302
Acute toxicity	Acute Tox.	3	H301
Specific target organ toxicity - single exposure	STOT SE	3	H336
Serious eye damage	Eye Dam.	1	H318
Skin corrosion	Skin Corr.	1	H314
Reproductive toxicity	Repr.	1B	H360
Flammable gases	Flam. Gas	1	H220
Chemically unstable gases	Chem. Unst. Gas	A	H230
Eye irritation	Eye Irrit.	2A	H319
Gases under pressure (compressed)	Press. Gas (Comp.)		H280
Reproductive toxicity	Repr.	1B	H360Fd
Acute toxicity	Acute Tox.	2	H330
Chronic hazardous to the aquatic environment	Aquatic Chronic	3	H412
Reproductive toxicity	Repr.	1B	H360FD
Reproductive toxicity	Repr.	1B	H360Fd